At Usona, our exploration of psychedelic compounds is guided by discovery through scientific rigor. Our Medicinal Chemistry team continues publishing impactful research articles in collaboration with scientists around the globe.
Usona Publications
Structure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice
Glatfelter, G. C.; Pottie, E.; Partilla, J. S.; Sherwood, A. M.; Kaylo, K.; Pham, D. N. K.; Naeem, M.; Sammeta, V. R.; DeBoer, S.; Golen, J. A.; Hulley, E. B.; Stove, C. P.; Chadeayne, A. R.; Manke, D. R.; Baumann, M. H. ACS Pharmacol. Transl. Sci. 2022, 5 (11), 1181–1196.
MDMA and Their Analogs as Therapeutics for Mental Disorder and Response Predictor
Kargbo, R. B. ACS Med. Chem. Lett. 2022, 13 (10), 1542–1544.
Restoration of Motor Function Post-Neurological Injury Using Serotonergic Agonist
Kargbo, R. B. ACS Med. Chem. Lett. ACS Med. Chem. Lett. 2022, 13 (9), 1397–1399.
Application of Deuterated N,N‑Dimethyltryptamine in the Potential Treatment of Psychiatric and Neurological Disorders
Kargbo, R. B. ACS Med. Chem. Lett. 2022, 13 (9), 1402–1404.
Assessment of Bioactivity-Modulating Pseudo-Ring Formation in Psilocin and Related Tryptamines
Lenz, C.; Dörner, S.; Trottmann, F.; Hertweck, C.; Sherwood, A.; Hoffmeister, D. ChemBioChem 2022, 23 (13), e202200183.
An Improved, Practical, and Scalable Five-Step Synthesis of Psilocybin
Sherwood, A. M.; Meisenheimer, P.; Tarpley, G.; Kargbo, R. B. Synthesis 2020, 52(05), 688–694.
Psilocybin: Crystal Structure Solutions Enable Phase Analysis of Prior Art and Recently Patented Examples
Sherwood, A. M.; Kargbo, R. B.; Kaylo, K. W.; Cozzi, N. V.; Meisenheimer, P.; Kaduk, J. A. Acta Crystallogr. Sect. C Struct. Chem. 2022, 78 (1), 36–55.
Reinforcing Effects of Synthetic Cathinones in Rhesus Monkeys: Dose-Response and Behavioral Economic Analyses
de Moura, F. B.; Sherwood, A.; Prisinzano, T. E.; Paronis, C. A.; Bergman, J.; Kohut, S. J. Pharmacol. Biochem. Behav. 2021, 202.
Our Mission and Vision
Get more information about our Medicinal Chemistry team and our work with synthetic processes and psychedelic compounds.
