At Usona, our exploration of psychedelic compounds is guided by discovery through scientific rigor. Our Medicinal Chemistry team continues publishing impactful research articles in collaboration with scientists around the globe.
Usona Publications
An Improved, Practical, and Scalable Five-Step Synthesis of Psilocybin
Sherwood, A. M.; Meisenheimer, P.; Tarpley, G.; Kargbo, R. B. Synthesis 2020, 52(05), 688–694.
Psilocybin: Crystal Structure Solutions Enable Phase Analysis of Prior Art and Recently Patented Examples
Sherwood, A. M.; Kargbo, R. B.; Kaylo, K. W.; Cozzi, N. V.; Meisenheimer, P.; Kaduk, J. A. Acta Crystallogr. Sect. C Struct. Chem. 2022, 78 (1), 36–55.
Reinforcing Effects of Synthetic Cathinones in Rhesus Monkeys: Dose-Response and Behavioral Economic Analyses
de Moura, F. B.; Sherwood, A.; Prisinzano, T. E.; Paronis, C. A.; Bergman, J.; Kohut, S. J. Pharmacol. Biochem. Behav. 2021, 202.
Discriminative-Stimulus Effects of Synthetic Cathinones in Squirrel Monkeys.
Wakeford, A. G. P.; Sherwood, A. M.; Prisinzano, T. E.; Bergman, J.; Kohut, S. J.; Paronis, C. A. Int. J. Neuropsychopharmacol. 2021, 24 (8), 656–665.
Psilocybin: Characterization of the Metastable Zone Width (MSZW), Control of Anhydrous Polymorphs, and Particle Size Distribution (PSD)
Kargbo, R. B.; Sherwood, A. M.; Meisenheimer, P.; Lenoch, K.; Abebe, S. ACS Omega 2022, 7 (6), 5429–5436.
Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin
Sherwood, A. M.; Halberstadt, A. L.; Klein, A. K.; McCorvy, J. D.; Kaylo, K. W.; Kargbo, R. B.; Meisenheimer, P. J. Nat. Prod. 2020, 83 (2), 461–467.
Chemoenzymatic Synthesis of 5-Methylpsilocybin: A Tryptamine with Potential Psychedelic Activity
Fricke, J.; Sherwood, A. M.; Halberstadt, A. L.; Kargbo, R. B.; Hoffmeister, D. J. Nat. Prod. 2021, 84 (4), 1403–1408.
Structure Elucidation and Spectroscopic Analysis of Chromophores Produced by Oxidative Psilocin Dimerization
Lenz, C.; Dörner, S.; Sherwood, A.; Hoffmeister, D. Chem. – Eur. J. 2021, 27 (47), 12166–12171.
Our Mission and Vision
Get more information about our Medicinal Chemistry team and our work with synthetic processes and psychedelic compounds.
