At Usona, our exploration of psychedelic compounds is defined by scientific rigor and discovery. Our Medicinal Chemistry team has published significant research articles in collaboration with scientists around the globe.
Usona Publications
Psilocybin: Characterization of the Metastable Zone Width (MSZW), Control of Anhydrous Polymorphs, and Particle Size Distribution (PSD)
Psilocybin: crystal structure solutions enable phase analysis of prior art and recently patented examples
Structure Elucidation and Spectroscopic Analysis of Chromophors Produced by Oxidative Psilocin Dimerzation
Lenz, C.; Dorner, S.; Hoffmeister, D. Chemistry: A European Journal. 2021.
Taking Different Roads: I-Tryptophan as the Origin of Psilocybe Natural Products
Lenz, C.; Sherwood, A. M.; Kargbo, R.; Hoffmeister, D. ChemPlus Chem. 2021.
Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin
Fricke, J.; Kargbo, R.; Regestein, L.; Lenz, C.; Peschel, G.; Rosenbaum, M.; Sherwood, A.; Hoffmeister, D. Chemistry: A European Journal. 2020.
Direct Phosphorylation of Psilocin Enables Optimized cGMP Kilogram-Scale Manufacture of Psilocybin
Kargbo, R.B.; Sherwood, A.M.; Walker, A.; Cozzi, N.V.; Dagger, R.E.; Sable, J.; O’Hern,K.; Kaylo,K.; Patterson, T.; Tarpley, G.; Meisenheimer, P. ACS Omega. 2020
Psilocybin Therapeutic Research: The Present and Future Paradigm
Kargbo, R. B. ACS Medicinal Chemistry Letters. 2020
Preparation and Characterization of Novel Crystalline Solvates and Polymorphs of Psilocybin and Identification of Solid Forms Suitable for Clinical Development
Greenan, C.; Arlin, J.-B.; Lorimer, K.; Kaylo, K.; Kargbo, R.; Meisenheimer, P.; Tarpley, G.; Sherwood, A. (Preprint – ResearchGate). 2020.
Our Mission and Vision
Get more information about our Medicinal Chemistry team and our work with synthetic processes and psychedelic compounds.
