At Usona, our exploration of psychedelic compounds is guided by discovery through scientific rigor. Our Medicinal Chemistry team continues publishing impactful research articles in collaboration with scientists around the globe.
Usona Publications
Synthesis and Characterization of 5-MeO-DMT Succinate for Clinical Use
Sherwood, A. M.; Claveau, R.; Lancelotta, R.; Kaylo, K. W.; Lenoch, K. ACS Omega 2020, 5 (49), 32067–32075.
Taking Different Roads: L‐Tryptophan as the Origin of Psilocybe Natural Products
Lenz, C.; Sherwood, A.; Kargbo, R.; Hoffmeister, D. ChemPlusChem 2021, 86 (1), 28–35.
Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin
Fricke, J.; Kargbo, R.; Regestein, L.; Lenz, C.; Peschel, G.; Rosenbaum, M. A.; Sherwood, A.; Hoffmeister, D. Chem. – Eur. J. 2020, 26 (37), 8281–8285.
Direct Phosphorylation of Psilocin Enables Optimized CGMP Kilogram-Scale Manufacture of Psilocybin
Kargbo, R. B.; Sherwood, A.; Walker, A.; Cozzi, N. V.; Dagger, R. E.; Sable, J.; O’Hern, K.; Kaylo, K.; Patterson, T.; Tarpley, G.; Meisenheimer, P. ACS Omega 2020, 5 (27), 16959–16966.
Psilocybin Therapeutic Research: The Present and Future Paradigm
Kargbo, R. B. ACS Medicinal Chemistry Letters. 2020
Preparation and Characterization of Novel Crystalline Solvates and Polymorphs of Psilocybin and Identification of Solid Forms Suitable for Clinical Development
Greenan, C.; Arlin, J.-B.; Lorimer, K.; Kaylo, K.; Kargbo, R.; Meisenheimer, P.; Tarpley, G.; Sherwood, A. (Preprint – ResearchGate). 2020.
Enzymatic Route toward 6-Methylated Baeocystin and Psilocybin
Fricke, J.; Sherwood, A.; Kargbo, R.; Orry, A.; Blei, F.; Naschberger, A.; Rupp, B.; Hoffmeister, D. ChemBioChem 2019, 20 (22), 2824–2829.
Clinical Consideration of 5-MeO-DMT
Sherwood, A.; Kaylo, K.; Kargbo, R.; Davis, A. K.; Lancelotta, R.; Uthaug, M.; Barrow, R. International Forum on Consciousness – Psychedelic Therapy and Society. 2019.
Our Mission and Vision
Get more information about our Medicinal Chemistry team and our work with synthetic processes and psychedelic compounds.
