At Usona, our exploration of psychedelic compounds is guided by discovery through scientific rigor. Our Medicinal Chemistry team continues publishing impactful research articles in collaboration with scientists around the globe.
Usona Publications
Discriminative-Stimulus Effects of Synthetic Cathinones in Squirrel Monkeys.
Wakeford, A. G. P.; Sherwood, A. M.; Prisinzano, T. E.; Bergman, J.; Kohut, S. J.; Paronis, C. A. Int. J. Neuropsychopharmacol. 2021, 24 (8), 656–665.
Psilocybin: Characterization of the Metastable Zone Width (MSZW), Control of Anhydrous Polymorphs, and Particle Size Distribution (PSD)
Kargbo, R. B.; Sherwood, A. M.; Meisenheimer, P.; Lenoch, K.; Abebe, S. ACS Omega 2022, 7 (6), 5429–5436.
Chemoenzymatic Synthesis of 5-Methylpsilocybin: A Tryptamine with Potential Psychedelic Activity
Fricke, J.; Sherwood, A. M.; Halberstadt, A. L.; Kargbo, R. B.; Hoffmeister, D. J. Nat. Prod. 2021, 84 (4), 1403–1408.
Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin
Sherwood, A. M.; Halberstadt, A. L.; Klein, A. K.; McCorvy, J. D.; Kaylo, K. W.; Kargbo, R. B.; Meisenheimer, P. J. Nat. Prod. 2020, 83 (2), 461–467.
Structure Elucidation and Spectroscopic Analysis of Chromophores Produced by Oxidative Psilocin Dimerization
Lenz, C.; Dörner, S.; Sherwood, A.; Hoffmeister, D. Chem. – Eur. J. 2021, 27 (47), 12166–12171.
Synthesis and Characterization of 5-MeO-DMT Succinate for Clinical Use
Sherwood, A. M.; Claveau, R.; Lancelotta, R.; Kaylo, K. W.; Lenoch, K. ACS Omega 2020, 5 (49), 32067–32075.
Taking Different Roads: L‐Tryptophan as the Origin of Psilocybe Natural Products
Lenz, C.; Sherwood, A.; Kargbo, R.; Hoffmeister, D. ChemPlusChem 2021, 86 (1), 28–35.
Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin
Fricke, J.; Kargbo, R.; Regestein, L.; Lenz, C.; Peschel, G.; Rosenbaum, M. A.; Sherwood, A.; Hoffmeister, D. Chem. – Eur. J. 2020, 26 (37), 8281–8285.
Our Mission and Vision
Get more information about our Medicinal Chemistry team and our work with synthetic processes and psychedelic compounds.
