Research

Publications

At Usona, our exploration of psychedelic compounds is defined by scientific rigor and discovery. Our Medicinal Chemistry team has published significant research articles in collaboration with scientists around the globe.

Usona Publications

Novel Psychotherapeutics – A Cautiously Optimistic Focus on Hallucinogens

Sherwood, A. M.; Prisinzano, T. E. Expert Review of Clinical Pharmacology. 2018.

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Enzymatic Route toward 6-Methylated Baeocystin and Psilocybin

Fricke, J.; Sherwood, A.; Kargbo, R.; Orry, A.; Blei, F.; Naschberger, A.; Rupp, B.; Hoffmeister, D.; Chembiochem. 2019.

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Clinical Consideration of 5-MeO-DMT

Sherwood, A.; Kaylo, K.; Kargbo, R.; Davis, A. K.; Lancelotta, R.; Uthaug, M.; Barrow, R. International Forum on Consciousness – Psychedelic Therapy and Society. 2019.

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Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin

Fricke, J.; Kargbo, R.; Regestein, L.; Lenz, C.; Peschel, G.; Rosenbaum, M.; Sherwood, A.; Hoffmeister, D. Chemistry: A European Journal. 2020.

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Preparation and Characterization of Novel Crystalline Solvates and Polymorphs of Psilocybin and Identification of Solid Forms Suitable for Clinical Development

Greenan, C.; Arlin, J.-B.; Lorimer, K.; Kaylo, K.; Kargbo, R.; Meisenheimer, P.; Tarpley, G.; Sherwood, A. (Preprint – ResearchGate). 2020.

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Psilocybin Therapeutic Research: The Present and Future Paradigm

Kargbo, R. B. ACS Medicinal Chemistry Letters. 2020

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Direct Phosphorylation of Psilocin Enables Optimized cGMP Kilogram-Scale Manufacture of Psilocybin

Kargbo, R.B.; Sherwood, A.M.; Walker, A.; Cozzi, N.V.; Dagger, R.E.; Sable, J.; O’Hern,K.; Kaylo,K.; Patterson, T.; Tarpley, G.; Meisenheimer, P. ACS Omega. 2020

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Taking Different Roads: I-Tryptophan as the Origin of Psilocybe Natural Products

Lenz, C.; Sherwood, A. M.; Kargbo, R.; Hoffmeister, D. ChemPlus Chem. 2021.

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