Research

Publications

At Usona, our exploration of psychedelic compounds is guided by discovery through scientific rigor. Our Medicinal Chemistry team continues publishing impactful research articles in collaboration with scientists around the globe.

Usona Publications

Swim in the Chiral Pool: MDMA and MDA Enantiomers from Alanine-Derived Precursors

Sherwood, A. M.; Burkhartzmeyer, E. K.; Williamson, S. E.; Faley, M. T. ACS Omega 2023, 8 (24), 22132–22137.

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5-MeO-DMT Modifies Innate Behaviors and Promotes Structural Neural Plasticity in Mice

Jefferson, S. J.; Gregg, I.; Dibbs, M.; Liao, C.; Wu, H.; Davoudian, P. A.; Woodburn, S. C.; Wehrle, P. H.; Sprouse, J. S.; Sherwood, A. M.; Kaye, A. P.; Pittenger, C.; Kwan, A. C. Neuropsychopharmacology 2023, 48 (9), 1257–1266.

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Psychedelics for Medicinal Use: How Will This Alter the Collective Laboratory Consciousness?

Cotten, S. W.; Strathmann, F. G.; Barrett, F. S.; Labay, L.; Mullally, J.; Sherwood, A. M.; Wiegand, F. Clin. Chem. 2023, 69 (4), 319–326.

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Structure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice

Glatfelter, G. C.; Pottie, E.; Partilla, J. S.; Sherwood, A. M.; Kaylo, K.; Pham, D. N. K.; Naeem, M.; Sammeta, V. R.; DeBoer, S.; Golen, J. A.; Hulley, E. B.; Stove, C. P.; Chadeayne, A. R.; Manke, D. R.; Baumann, M. H. ACS Pharmacol. Transl. Sci. 2022, 5 (11), 1181–1196.

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MDMA and Their Analogs as Therapeutics for Mental Disorder and Response Predictor

Kargbo, R. B. ACS Med. Chem. Lett. 2022, 13 (10), 1542–1544.

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Restoration of Motor Function Post-Neurological Injury Using Serotonergic Agonist

Kargbo, R. B. ACS Med. Chem. Lett. ACS Med. Chem. Lett. 2022, 13 (9), 1397–1399.

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Application of Deuterated N,N‑Dimethyltryptamine in the Potential Treatment of Psychiatric and Neurological Disorders

Kargbo, R. B. ACS Med. Chem. Lett. 2022, 13 (9), 1402–1404.

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Assessment of Bioactivity-Modulating Pseudo-Ring Formation in Psilocin and Related Tryptamines

Lenz, C.; Dörner, S.; Trottmann, F.; Hertweck, C.; Sherwood, A.; Hoffmeister, D. ChemBioChem 2022, 23 (13), e202200183.

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