Depression can rob people of their joy in life. Moreover, by damaging the brain and body, it may rob people of life itself through reducing patients’ life expectancy by an average of 10 years. Because depression is so common and because so many patients do not adequately respond to currently available treatments, this condition is the leading cause of disability worldwide. For all of these reasons, we currently face no greater health challenge than the need to find new and more effective treatments for depression.
Usona Institute is currently in the planning phases for our multi-site Phase 2/Phase 3 clinical research program focused on psilocybin as a treatment for major depressive disorder (MDD). For more information on our clinical trials, please follow the link below:
Investigator’s Brochure for Psilocybin
The Investigator’s Brochure for psilocybin is a detailed compendium of information on psilocybin’s pharmacology, safety, and efficacy. Consistent with our open science approach, this document will be openly shared with other researchers for use in their own regulatory submissions and clinical trials, under a Creative Commons license. To view the document, please see: Usona Investigator’s Brochure for Psilocybin
Cancer-related depression and anxiety
Studies in healthy adults
Chapters & Books
“Use of the Classic Hallucinogen Psilocybin for Treatment of Existential Distress Associated with Cancer.” 2013. Grob CS, Bossis AP, Griffiths RR. In Psychological Aspects of Cancer, (pp. 291–308). Carr BI, Steel JL (Eds). Springer Science and Business Media LLC, New York.
Frontiers of Psychedelic Consciousness: Conversations with Albert Hofmann, Stanislav Grof, Rick Strassman, Jeremy Narby, Simon Posford, and Others. By David Jay Brown, 2015.
Higher Wisdom: Eminent Elders Explore the Continuing Impact of Psychedelics. Edited by Roger Walsh and Charles S. Grob, 2005.
Psychedelic Explorer’s Guide: Safe, Therapeutic and Sacred Journeys. 2011. James Fadiman. Park Street Press.
Sacred Knowledge: Psychedelics and Religious Experiences. By William A. Richards, 2015.
The Psilocybin Solution: The Role of Sacred Mushrooms in the Quest for Meaning. By Simon G. Powell, 2011.
The goal of Usona’s grant program is to advance knowledge about the potential therapeutic effects of psilocybin and other consciousness-expanding medicines, consistent with Usona’s overall mission and goals. Grant requests must be of high scientific caliber, and are evaluated on a rolling basis. For more information, please contact us.