Depression and anxiety can rob people of their joy in life. Moreover, by damaging the brain and body, they may rob people of life itself, reducing patients’ life expectancy by an average of 10 years. Because depression and anxiety are so common and because so many patients do not adequately respond to currently available treatments, these conditions are the second leading cause of disability worldwide. For all of these reasons, we currently face no greater health challenge than the need to find new and more effective treatments for depression and anxiety.
Usona Institute is currently in the planning phases for FDA phase 2 and phase 3 multi-site research studies focused on psilocybin as a treatment for depression and anxiety, including in cases of cancer-related psychological distress.
Investigator’s Brochure for Psilocybin
The Investigator’s Brochure for psilocybin is a detailed compendium of information on psilocybin’s pharmacology, safety, and efficacy. Consistent with our open science approach, this document will be openly shared with other researchers for use in their own regulatory submissions and clinical trials, under a Creative Commons license. To view the document, please see: Usona Investigator’s Brochure for Psilocybin
Cancer-related depression and anxiety
Studies in healthy adults
Chapters & Books
“Use of the Classic Hallucinogen Psilocybin for Treatment of Existential Distress Associated with Cancer.” 2013. Grob CS, Bossis AP, Griffiths RR. In Psychological Aspects of Cancer, (pp. 291–308). Carr BI, Steel JL (Eds). Springer Science and Business Media LLC, New York.
Frontiers of Psychedelic Consciousness: Conversations with Albert Hofmann, Stanislav Grof, Rick Strassman, Jeremy Narby, Simon Posford, and Others. By David Jay Brown, 2015.
Higher Wisdom: Eminent Elders Explore the Continuing Impact of Psychedelics. Edited by Roger Walsh and Charles S. Grob, 2005.
Psychedelic Explorer’s Guide: Safe, Therapeutic and Sacred Journeys. 2011. James Fadiman. Park Street Press.
Sacred Knowledge: Psychedelics and Religious Experiences. By William A. Richards, 2015.
The Psilocybin Solution: The Role of Sacred Mushrooms in the Quest for Meaning. By Simon G. Powell, 2011.